Ivermectin Injection is an anthelmintic drug indicated for internal and external parasitic infestations in livestock.
Ivermectin Injection / Ivermac®
What is Ivermectin?
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Antiparasitic |
Therapeutic Class |
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Camel , Cow , Goat , Pig, Sheep |
Target Species |
|
10mg Ivermectin |
Active Ingredients |
Ivermectin
Avermectin Injection is an antiparasitic drug used to treat internal and external parasites in small and large animals, such as cows and sheep. This drug is used in the treatment and prevention of nematodes such as gastrointestinal roundworms, grubs, lungworms, sucking lice and mange mites.
Avermectin is within the family of medicines called anthelmintics. It is derived from Streptomyces avermitilis's fermented products. Avermectin works by inhibiting the function of aspects of the nervous system within the parasite. This leads to its paralysis and then the death of the parasite.
It is important to note that Avermectin Injection is for veterinary purposes only.
Indications :
This medication is used to combat the following parasites:
Dosage and Administration :
It is administered subcutaneously only, and the recommended therapeutic dose is 1 ml per 50 kg of body weight equivalent to 10 mg of ivermectin per 50 kg of body weight.
Treatment of cattle infected with skin bots should be carried out as soon as possible at the end of the botfly breeding season, either before the larval stages develop or after they are fully developed.
Precautions :
Do NOT use Ivermectin Injection for an animal that:
There are known interactions between this medication and other drugs, including benzodiazepines, ketamine, spinosad, amiodarone, carvedilol, clarithromycin, cyclosporine, and ketoconazole.
Compounds that can enhance the effects of Ivermectin, such as barbiturates, tranquilizers, and sedatives, should be used with caution to avoid potential toxicity. Concurrent use of cholinergic agonists can also lead to increased risk of ivermectin-related neurotoxicity.
This drug may cause false-negative results for animals with an occult heartworm infection. Conduct heartworm testing before starting the treatment with Ivermectin and repeat the test after the drug's effect has waned to ensure accurate results. Ivermectin may also alter liver enzymes and other blood parameters, potentially affecting a variety of blood tests.
Only use a subcutaneous injection for cattle and swine. Do not administer Ivermectin Injections through the IV or IM route.
Side Effects :
As with all pharmaceuticals, some unwanted effects can occur from the use of Ivermectin Injection.
Some common side effects may include pain or discomfort at the site of injection.
Serious side effects may include:
If side effects are observed following the administration of this drug, seek veterinary advice. Minor issues like discomfort at the injection site often subside without intervention, but professional guidance should be sought if symptoms persist.
For severe reactions, such as signs of allergic responses or neurotoxicity, immediate veterinary intervention is needed. A veterinarian may administer treatments such as corticosteroids to manage inflammation or epinephrine for severe allergic cases.
Ivermectin is typically used by veterinary professionals in animals such as:
It's used to treat certain parasitic infections. It is indicated for the treatment of:
This drug is recommended for dogs and cats, as well as livestock animals such as camels, cows, goats, sheep, and pigs.
This medication has been manufactured as a liquid, which is packaged in a vial. It is intended to be administered by subcutaneous injection.
The withdrawal period is 28-42 days. Do not use this medicine for lactating dairy cows, as the withdrawal time is unknown.
While Ivermectin can sometimes be used with other medications, it is important to avoid drug interactions. Always inform the veterinarian about any other treatments the animal is receiving.
The drug works by interfering with the nervous system and muscle function of parasites. It enhances the release of a neurotransmitter that causes paralysis and death, thereby clearing parasites from the animal's body.
There is a potential for the development of resistance if the drug is used repeatedly or improperly. The drug should be used as part of an integrated parasite management program and rotated with other classes of dewormers.
Ivermectin may not be effective against all stages of parasites or all types of parasites. For example, it may not work against certain external parasites like ticks, or against certain flukes or tapeworms. A veterinarian can provide guidance on the appropriate use and limitations.
Ivermectin should be used with caution in certain breeds of dogs like Collies and other herding breeds, which are more sensitive to the drug due to a genetic mutation (MDR1 gene mutation) that affects drug transport across the blood-brain barrier. A veterinarian should perform genetic testing before administering the drug to these breeds.
This medication should be stored in a dark, dry location between 15-25°C. The vial should be sealed tightly.
For cattle, it is typically administered at a dosage of 200 micrograms per kilogram of body weight to control parasites such as gastrointestinal roundworms, lungworms, and lice.
Sheep and goats are usually given Ivermectin at a dose of 200mcg per kilogram of body weight to treat parasitic infections such as gastrointestinal roundworms, lungworms, and nasal bots.
In pigs, the usual dose for Ivermectin is 300mcg per kilogram of body weight, which helps in the control of gastrointestinal roundworms, lungworms, lice, and mange mites.
Yes, depending on the type of parasite and the animal's health status. The dose may be adjusted for treating external parasites like lice and mites compared to internal parasites.
Seek immediate veterinary attention. Symptoms of overdose may include lethargy, depression, vomiting, tremors, and seizures. Treatment is supportive and symptomatic, as there is no specific antidote for ivermectin toxicity.
Refer to a veterinary doctor or pharmacist for guidelines on dosage.
